The three most-used SARMs ranked. Anabolic effect vs HPG suppression vs cycle-recovery time.
High-potency SARM, near testosterone-level anabolic signal. Hepatotoxicity reports in users.
Read full guide → Selective androgen receptor modulatorPotent SARM — clean, strength-focused. Strongest HPG suppression of the SARMs.
Read full guide → Selective androgen receptor modulatorThe most-studied SARM. Mildest profile — bridging tool for recomp and injury recovery.
Read full guide →| RAD-140 | LGD-4033 | Ostarine | |
|---|---|---|---|
| Anabolic effect | Strong (near-test) | Strong | Mild |
| Suppression | Heavy | Heavy | Mild |
| Typical dose | 10-20 mg / day | 5-10 mg / day | 15-25 mg / day |
| Cycle | 8-12 weeks | 8-12 weeks | 8-12 weeks |
| PCT required? | Yes (Nolvadex) | Yes (Nolvadex/Enclomiphene) | Sometimes |
| Best for | Mass, strength | Lean strength, recomp | Recomp, healing |
| Side-effect flag | Hepatotoxicity reports | Strong HPG suppression | Mildest profile |
| Human trial data | Sparse | Phase II | Phase III (cachexia) |
There is no free lunch with SARMs. The compounds that produce the strongest anabolic effect (RAD-140, LGD-4033) also produce the heaviest HPG suppression. Ostarine, the mildest, also has the weakest anabolic effect. Pick based on what side of that tradeoff matters more to you.
Recomp cycles, bridge cycles between AAS cycles, injury recovery, first-time SARM users. The most studied SARM (FDA Phase III for cancer cachexia), the mildest suppression, and the lowest reported side-effect rate. Often run without PCT at 15 mg / day, though SERM PCT is still advisable.
Lean strength, recomp with more aggression than Ostarine can deliver, clean dryness profile. Suppresses HPG hard — needs a full 4-week PCT with Nolvadex or Enclomiphene. Sourcing risk: heavily counterfeited.
Maximum anabolic effect SARMs can offer, near-testosterone levels of muscle and strength gains. The hepatotoxicity case reports (a handful of published liver-injury cases) and aggressive HPG suppression mean this is the SARM with the highest risk profile. Full PCT mandatory.
Epti lets you log your protocol — every dose, side-effect, and outcome on one timeline. The only way to know which works for you.